Pharmacotherapy serves an important and increasing role in treatment of specific psychopathology in youth. While introductory pharmacotherapy institutes are helpful in orienting clinicians to the major psychiatric disorders and first line treatment, they do not provide adequate information for complicated cases requiring advanced psychopharamacology, including monotherapy of novel agents or combined medication strategies. This Institute provides a higher level of understanding of medications in refractory or more complicated children and adolescents with psychopathology.